2-CB: the Effects, the Comedown, and How Long it Lasts

Anecdotal reports claim the “come-down” period of 2C-B typically lasts between 2 and 4 hours. During this comedown, some people may experience a bad trip, causing them to “crash” or become depressed. 2C-B is a Schedule I drug with no accepted medical drug use and a high potential for addiction. Possession of 2C-B is https://sober-house.org/psychedelic-and-dissociative-drugs-national-2/ punishable by up to 7 years in prison, a fine, or both. 2C-B will stay in your oral fluid for hours.With that said, the substance is extremely hard to detect and standard drug tests are not capable of that. Research chemicals, such as 2C-B-Fly, are similar to 2C-B as far as their effects and chemical structure.

1. If you are in a crisis or if you or any other person may be in danger or experiencing a mental health emergency, immediately call 911 or your local emergency resources.
2. Therefore, there is virtually no way to know what your trip will feel like.The only way to truly know what 2C-B feels like is to take 2C-B.2C-B will most likely give you a pleasant experience.
3. This guide includes comprehensive ketamine resources containing books, studies and more.
4. 2C-B is a Schedule I drug with no accepted medical drug use and a high potential for addiction.

Always Test Your Substances

Most of the responses we’ve received throughout our 2C-B survey had a positive sentiment. Many people taking part in our surveys and in the psychedelic community at large consider 2C-B to be their favorite psychedelic. 2C-B reached mainstream popularity sometime after 1985 when MDMA was officially banned. But there’s another popular psychoactive substance that’s been residing in the shadows since the 1980s.

-B: Effects, Dosage, & Safety

2C-B is most often used in place of MDMA at concerts, parties, or music festivals. The stimulating and euphoric effects make people feel more social and engaged, it creates a strong sense of empathy and connectedness with other people, and it won’t inhibit your ability to sleep at the end of the night. The effects of 2C-B have been described as a combination between LSD and MDMA — but this is a simplification. In one of his books — PiHKAL (phenethylamines I Have Known And Loved) — he listed 2C-B among his “magic half dozen”.

-B Is the Drug Taking Over the UK’s Clubs

The qualities of 2C-B made it popular as a sex-enhancement drug in the 80s. The German pharmaceutical company Drittewelle started producing the drug under the name “Nexus.” It was sold in sex shops as a way to boost libido, sexual connection and increase stamina and energy. 2C-B is still considered by many to be the best psychedelic to use during sex of all time. Certain poly-drug mixes can increase risks, and it is not advised to mix MAOI antidepressants, lithium, or tramadol with 2C-B. Cannabis and amphetamines are also known to interact negatively, possibly intensifying the experience and increasing users’ anxiety, paranoia and negative thought loops. If you are set on experimenting with the 2C-B and cannabis combination, keep both doses lower than usual and spread out your cannabis intake by at least an hour or more before re-dosing.

You can do so using a Marquis Reagent Test Kit; 2C-B is the only substance known to turn the reagent a bright greenish-yellow color according to The Third Wave. Properly dosing 2C-B is crucial for having a safe and fun experience, and most folks stay in the 5 to 25 mg range. The experience definitely changes with the dose, with many people reporting manageable empathogenic feelings at lower doses of 5 to 15 mg, and more psychedelic and visual experiences at doses in the 15 to 25 mg range and above. In a similar manner to other NSPs and some psychedelics, the human pharmacokinetics of 2C-B has not yet been fully resolved.

How do people take it?

Most psychedelics work by activating the 5-HT2A serotonin receptors. This is the primary mechanism of action employed by substances, including LSD, DMT, and psilocybin. Mixing 2CB with other psychedelics like LSD, mescaline, or magic mushrooms can lead to much stronger hallucinations. Anecdotal reports on sites like Reddit, as well as through our own surveys, suggest some people prefer to take large doses of the drug (over 50 mg) — without experiencing any severe side effects.

Anecdotally, in two subjects involved in a road accident, 2C-B has been identified in blood at concentrations of 1.6 and 14 ng/ml together with amphetamine (Busardò et al., 2017). As with all psychedelic drugs, it’s very hard to predict how you’ll feel when you take a 2C drug – and some 2Cs cause more psychedelic effects than others. dangers of quitting alcohol cold turkey The more you take, the more intense and uncontrollable the experience will be. 2C drugs are considered to have low addiction potential, but the long-term effects of psychoactive substances like 2C-B have not been well-studied. What makes the effects of 2C-B particularly interesting is the chemical crossroads it finds itself in.

Another interesting side effect, or lack thereof, is that many users also report being able to eat and sleep with ease after the experience—something they’ve struggled with after a night with MDMA or LSD. Plus, at low and moderate doses, many report still being able to perform sexually (and really enjoying it), which is pretty famously hard on MDMA without the help of drugs like Viagra. By the early Nineties, Americans had become the world’s largest consumer of Nexus, often buying packs at sex and head shops and eating four or five pills (the equivalent of 20–25 mg) for its psychedelic effects.

In addition, 2C-B is metabolized by monoamine oxidase, an enzyme in the brain. Some antidepressant drugs work by inhibiting this enzyme, and 2C-B should be avoided by individuals who use these medications. Using alcohol or other illicit substances at the same time as 2C-B can increase the risks posed by 2C-B use.

While hallucinogens are not typically addictive, 2C-B’s stimulant effects can lead to addiction, causing long-term negative effects. People may depend on the drug to achieve positive feelings, neglecting aspects of their daily lives to acquire or use it. Because the beginning of the high is painful, most people report having an unpleasant experience with the drug. According to the 2019 Global Drug Survey, darknet purchases of the alcohol and anxiety drug significantly increased over 5 years, along with other drugs like DMT and ketamine. 2C-B is a novel psychoactive drug that alters a person’s thought process, sense of time, and emotions. In the spiritual community, there are mixed opinions on this.You will not be able to retain these states of consciousness unless you put in a lot of work in your “sober” life.However, that doesn’t mean that psychedelics cannot be helpful.

It was invented in 1974 by a man named Alexander Shulgin — the godfather of MDMA and creator of the entire 2C- family of substances. Because there’s so many anecdotal reports that 2C-B has relatively few negative side effects, there’s some speculation that it could be a reasonable choice (or alternative to MDMA) in psychedelic-assisted therapy. And although it was used by some therapists before it was outlawed in the mid-Nineties, the research into its safety and application is scant. According to PiHKAL, 2C-B lasts between four and eight hours, and that’s pretty in line with what the 31 people who took my survey reported. Most said 2C-B lasted between four and six hours, depending on the dose, with a notable comedown somewhere between the three and six-hour mark. Moore told me the experience lasted longer than he expected, with a long comedown.